Ingredients approved by the Japanese Orthopaedic AssociationClinical evidence: Effectively improve joint problems in 7 days: improve flexibility, joint comfort, and improve joint discomfort 6 major bone-protecting ingredients: including 5-LOXIN® (Boswellia serrata resin extract), HAS-II hyaluronic acid inducer, Water Chestnut Extract,Salmon nasal cartilage extract (containing proteoglycans), Curcumin extract powder, and MSM (methylsulfonylmethane), which work together to maintain joint health.According to Japanese Knee Osteoarthritis Measure, a questionnaire on the quality of life of Japanese patients with osteoarthritis supervised by by the Japanese Orthopedic Association.The Japanese Anatomical Orthopedic Association, and the Japanese Orthopedic Association, taking HAS-II can improve the quality of life: relieve joint discomfort and stiffness, and reduce the impact of knee joint problems on daily activities.. Ingredient: 5-Loxin (Boswellia serrata Extract) (Made in India), Starch, HAS-II (Chicken Feet Extract), Methylsulfonylmethane (MSM), Salmon Nasal Cartilage Extract (Contains Proteoglycan), Water Chestnut Extract, Curcumin Extract Powder, HPMC, Calcium Stearate (Emulsifier), Fine Silica, Colorant (Silica), (Contains Salmon, Chicken and Gelatin in some cases)