Brand from Japan: LION. This is the only medicated toothpaste in Japan that contains the active ingredient enzyme.It can break down and remove tartar that causes various risks in the oral cavity.Enzymes can break down and remove plaque in corners that a toothbrush cannot reach.At the same time, yellow plaque accumulated on the tooth roots can be removed by brushing, making the teeth whiter.Contains high concentration of fluoride (1450ppm) and adheres tightly to the tooth root.Kills bacteria and prevents bad breath, whitens teeth and prevents tartar buildup.Refreshing and elegant mint flavor.How to use:Apply an appropriate amount to a toothbrush for use.