Brand from Japan: LION. This is the only medicated toothpaste in Japan that contains the active ingredient enzyme.It can break down and remove tartar that causes various risks in the oral cavity.Enzymes can break down and remove plaque in corners that a toothbrush cannot reach.In addition, the enzyme will remain on the surface of the teeth after brushing, preventing dental plaque from sticking.An all-in-one formula with seven functions, focusing on seven major life risks at the same time.For example, it can take care of tooth decay, periodontal disease, etc. and keep gums healthy.Contains high concentration of fluoride (1450ppm) to protect teeth.Prevents stinging caused by allergies.Kills bacteria and prevents bad breath, whitens teeth and prevents tartar buildup.How to use:Apply an appropriate amount to a toothbrush for use.